Notably, in a recent pre-post intervention clinical trial, chronic kidney disease (CKD) patients with vitamin K deficiency underwent four weeks of supplementation with menaquinone-7. So I started to use the tread mill for two 15 minutes periods a day. Low testosterone in men is considered a factor in some age-related diseases. Although vitamin K has been around for decades, dietary recommendations have been overshadowed by the nominal amount of K1 required for healthy blood clotting—and have ignored the optimal amounts of vitamin K2 needed to maintain healthy bones and arteries at all stage of life. Vitamin K2 supplements are safe, and there have been no reported side effects, even at high doses. 30 Foods High In Vitamin B5 (Pantothenic Acid), In a study consisting of 16,047 women, those who consumed the most vitamin K2 had a lower risk of developing heart disease (, Vitamin K2 can inhibit or potentially, reduce the progression of atherosclerosis (calcification of the arteries) (, Daily doses of vitamin K2 prevent the progression of atherosclerotic plaque in animal studies (. It’s known to have actions in the kidney, and lungs too. Vitamin K2 Basics. Vitamin K2 seems to be in the spotlight lately, and for good reason. 3 Major Benefits of Vitamin K2. It helps eliminate calcium from locations where it should not be, like in the soft tissues and arteries. This potent apoptotic effect was observed on human bladder cancer cells but NOT on normal cells. Since CRP can be a risk marker for a wide range of diseases, the researchers concluded that greater vitamin K2 intake might lower the risk for diseases other than rheumatoid arthritis (26). Once again, this association was not present for vitamin K1 (17). Deposits calcium on bones and prevents calcium loss from bones. A vitamin that can unlock heart disease by reversing it and preventing it … we’re breaking down Vitamin K2 today! Vitamin K2, and MK-7, in particular, are important for incorporating calcium properly into quickly developing bone structure. I like the idea that MK4 and MK7 can have different (but equally beneficial) effects in the body. I used to suffer from Raynaud’s Phenom. Vitamin K has two main forms: vitamin K1 and vitamin K2. Vitamin K2 suppressed the growth of human bladder cancer cells in mice, which was further confirmed by vitamin K2-induced apoptosis. Anyhow there are some of the delusions that our body can convert K1 to K2, animals can convert K1 to K2, but humans need food containing K2 or … What’s good for our teeth is good for our whole body, How to Cure Tooth Decay | A Dentist’s Guide to Reverse Cavities in 3 Steps, The Infant Dental Check: Newborn Baby Head Shape, A Guide to Straighten Your Kid’s Teeth at Home, Is My Baby Tongue Tied? That is an interesting point… perhaps this could suggest that MK-4 plays some sort of protective role in the liver? Thanks for majestic information. By any chance is a deficiency of it related to Raynauds? Let me tell you about vitamin K2 benefits. Protects the heart; Lowers risk of fracture, bone loss, and osteoporosis; Promotes dental health; May improve insulin resistance; Fights inflammation In addition, a randomized trial featuring 379 healthy men and women demonstrated that individuals with poor vitamin K status had higher concentrations of the pro-inflammatory cytokines CRP and interleukin-6 (IL6) (27). Both forms of vitamin K are vital to your body’s blood clotting process — though K2 may be better at it. Follow. They may even have an antioxidant role in the brain itself. However, there are numerous educated assumptions that we can make. Interestingly, this MK-7 supplementation resulted in significant reductions in the calcification of the patients’ blood vessels (36). Vitamin K has a range of structures with "K1; phylloquinone" and "K2; menaquinone" being the first major difference. Posts: 1 Joined: Apr 06, 2019. VitaMK7 MULTI BENEFITS FOR EVERY SEASON OF LIFE . I do not take any medication for diabetes now but I gained some weight and it went from A1C 6.4 to 6.8. Testosterone is a hormone present in greater quantities in men than women. However, vitamin K-2 may also protect against certain forms of cancer and heart disease. Keeps Blood Clotting Normally There is accumulating evidence that vitamin K2 may play a role in the health of our kidneys. Osteocalcin depends on vitamin K2 for activation via carboxylation ( 11 ). Vitamin K2 Benefits. Vitamin K activates a … Pseudoxanthoma elasticum: A condition where the mineralization of skin and premature wrinkles occur. Health Benefits Of Vitamin K2. Vitamin K2 has shown other possible benefits relevant to the 40-plus crowd. Vitamin K2 may prevent wrinkles and reverse aging. Compared to many other vitamins, the roles and health benefits of vitamin K2 were only recently discovered. Kanaaz Pereira, Connect Moderator … For instance, a study analyzed the impact of increasing vitamin K2 intake in 158 female patients with a mean age of 62.5 years old. It also directs calcium to the place that needs it the most: bone (23). It happens when old bone mass removal is not compensated by new bone mass addition. Learn more here. Vitamin K2 activates two key proteins in the body. Benefits of vitamin K2 Management of Osteoporosis. In this Vitamin K2 Review Our Main Focus is Vitamin K2’s Benefit in Binding Calcium to the bones. Be enlightened as to how this mostly unknown vitamin appears to be vital, especially in helping to regress arterial calcification. Polycystic ovary syndrome is characterized by an overproduction of certain steroids such as testosterone and DHEA sulfate (DHEAS). Anyhow there are some of the delusions that our body can convert K1 to K2, animals can convert K1 to K2, but humans need food containing K2 or … People with polymorphisms for matrix-GLA protein also have higher risk of kidney stones. Since Vitamin K plays an essential role in blood clotting and research has shown it is important for bone health, let’s take a closer look at the health benefits of Vitamin K2. It was also postulated that vitamin K2 could reduce insulin resistance and the risk of type 2 … “Vitamin K2 as MK-7 is the only compound to date shown to impact arterial calcification through its activation of MGP, which is why it is garnering attention from the medical community as a potential therapy,” says Christopher Speed, Senior Vice President of Global Sales and Marketing with NattoPharma, the world leaders in vitamin K2 research and development. I no longer suffer from it. Calcium is important for strengthening bones and overall skeletal health. MenaquinGold® and Best Probiotics HU58, HU36, SC208, SC307 and SC 109. While researchers still have more to learn about the benefits of vitamin K2, it appears to be an important vitamin for human health. Given the way vitamin K2 works, there might be a mechanism there, but I don’t really know to be honest. The most important benefits of vitamin K2 supplements include the following: Improve bone health. Additionally, the Rotterdam Study showed that menaquinone (K2) decreased the risk of arterial calcification and cardiovascular disease mortality. Activated proteins may increase insulin sensitivity, the core problem in type-II diabetes. https://www.synergialifesciences.com. In artery and heart cells, if calcium levels are too high within a cell, the cell actually changes physically and will die. Vitamin K2 also reduced the inflammation markers in the body in such cases. You also find K2 in animal products like fatty fish and grass-fed beef, or in fermented foods like natto. In addition to protecting your heart, vitamin K2 supports healthy circulation and benefits blood clotting. Vitamin K2 plays an essential role in bone metabolism, and studies suggest that it can help prevent osteoporosis and fractures. As we’ve discussed in this series, the benefits of Vitamin K2 begin from inside your teeth, right through to your gums, heart and bones. Its role could be key in the neuro-degenerative process. Regarding potential mechanisms, in a recent cell (test tube) study, researchers showed that vitamin K2 could inhibit cell proliferation and induce apoptosis (cell death) (19). Vitamin K is fat soluble and best known traditionally for its necessary role in helping blood clot properly. The most obvious role of Vitamin K2 on the brain may be prevention of cardiac embolism or stroke. Vitamin K is necessary for many reasons, including the following benefits. Health Benefits Of Vitamin K2. Overall, it seems to prevent oxidative stress and inflammation in the brain. Here’s a more thorough explanation of the benefits of vitamin K2: 1. Vitamin K1 is generally the preferred form of vitamin K because it is … This hormonal imbalance includes the over-production of testosterone (29, 30). Vitamin K2 Benefits. Vitamin K has been shown to help brain function 1 & development (especially in younger children), support healthy bones & teeth, and even help your body prevent cancer, coronary artery disease, and heart disease!. New studies are looking at another subtype called vitamin K2 and its effect in synergy with Vitamin D3 on various health factors. But new research has discovered a range of other benefits relating to increased vitamin K2 intake when it comes to improving health and longevity. Benefits of Vitamin K2. There are many different forms of vitamin K2, but the two primary forms found in food are: On the other hand, vitamin K1 (phylloquinone) mainly occurs in plant foods, predominantly in dark green vegetables such as collard greens and spinach. Collagen and elastin are two of the components of skin that give it firmness and elasticity. Natural Vitamin K2-7 is very important for healthy life e.g. From what I understand you can’t over-do it, as the body gets rid of excess. In short; a greater intake of vitamin K2 may improve insulin sensitivity, but the evidence for this effect is unclear, and more research is necessary. Firstly, as a result of vitamin K2’s impact on calcium absorption, this should also confer dental health benefits, since calcium is a vital mineral for tooth mineralization (20). Most supplements I’ve seen are around 100ug. I think between 100-200 ug daily is ok. This protein is activated only in the presence of Vitamin K2. Due to this emerging research, vitamin K2 has been reborn with a new vigor, and it is starting to get the attention it deserves in the medical world. For example, initial research from the Heidelberg cohort of the European prospective investigation into cancer and nutrition (EPIC-Heidelberg) study suggested there might be an inverse association between menaquinone (particularly from dairy) and prostate cancer (17). Vitamin K2 (MK-4) positively correlates with sulfatides and sphingomyelin, two brain-protective components . While children and adolescents require vitamin K2 for bone development to ensure healthy physical growth, adults aged 60 and older around the globe are leading more active lifestyles and taking on greater responsibility for their health. All Rights Reserved. One risk factor for kidney stones is excess Vitamin D, as demonstrated in lifeguards. Recently, however, research has begun to demonstrate that vitamin K1 is likely more involved in blood clotting than is vitamin K2. Ongoing research has confirmed that vitamin K2’s role in human health extends beyond what’s possible with K1. On this note, research shows that osteocalcin is found in inflamed pulpal tissues, suggesting that it may play a regenerative role. Vitamin K2 and Calcium (CAC) Score; oubobcat @oubobcat. One of the major benefits of vitamin K2 is that it activates osteocalcin, which is a protein hormone made by the bones. The exact type of supplement (form of vitamin K2) being used could potentially explain the contrast between these different studies. Dr Steven Lin’s book, The Dental Diet, is available to order today. Overall, it seems a good dietary intake of Vitamin K2 is vital for optimal brain function and preventing degenerative disease. The benefits of vitamin K2 are plenty but underappreciated. First real dentist? TQ. Ongoing research has confirmed that vitamin K2’s role in human health extends beyond what’s possible with K1. How much of K-2 to take daily? A little-used supplement called vitamin K2 offers enormous benefits for both cardiovascular and bone health. Our bodies need calcium to build and maintain bones. This vitamin can be separated into two categories: MK-4 (menaquinone-4), a type of vitamin K2. Vitamin K2 Benefits. Since vitamin K is fat-soluble, eating the spinach alongside a source of fat (butter) led to a threefold improvement in the absorption rate (40). The benefits of vitamin K2 are plenty but underappreciated. His book 'The Dental Diet', will be released on January 18'. Additionally, vitamin K2 is said to protect against some forms of cancer. Your email is safe with me. Vitamin K2 is a fat-soluble vitamin that has some notable differences from vitamin K1. For example, a further systematic review of controlled trials found that vitamin K2 supplementation did not affect insulin sensitivity (34). Osteoporosis is a disease in which the bones mass reduces over time and they become weak. Vitamin K2 shares a lot of the same vital roles in the body as vitamin K1. As Dr. Kate has already noted, more research needs to be done on what foods are high in this wonder nutrient, but based on what we know right now, here are the foods to make sure you are consuming frequently to obtain the full benefits of Vitamin K2. One study on Vitamin K2 indicated that it can reduce the risk of prostate cancer by 63 percent. Vitamin K2 may have another key benefit through potentially lowering markers of inflammation within the body. Another one of key benefits of Vitamin K2 benefits is that it activates MGP which binds to free floating calcium, preventing it from being deposited in vessels and arteries. If it is an issue for someone you know, this might be something worth discussing with a doctor/specialist. A lesser source is vitamin K2, or menaquinone, which occurs in some animal-based and fermented foods. Some of these “consequences” include vascular calcifications, bleeding, and higher mortality (37). https://www.synergialifesciences.com/natural-vitamin-k2-menaquingold.html, Your email address will not be published. A Danish scientist named Henrik Dam made the discovery of the vitamin K group of vitamins in 1929 (1). What is Vitamin K2? Vitamin K2 induced mitochondria-related apoptosis in human bladder cancer cells via ROS-JNK/p38 MAPK signal pathways. Additionally, chronic kidney disease patients typically have a subclinical vitamin K deficiency, suggesting that this group may benefit from a greater intake of the vitamin (38). When it comes to vitamin K2 side effects, you need to learn about the basics of vitamin K2 first. Bone health, Diabetes management and Muscle health etc. Vitamin K2 benefits. To receive free updates on functional oral health from Dr. Lin, subscribe to his newsletter below. Important: this post will focus specifically on the benefits of vitamin K2. Commenting on the relationship between MK4 and insulin resistance, my own experience is that MK4 simply doesn’t work if you have serious insulin resistance–all you get is side-effects! Vitamin K2 is linked to calcium metabolism. Without enough vitamin K, blood clotting can be inhibited, increasing the risk for excessive blood loss upon injury. Although the precise absorption rate of vitamin K2 is not known, the consumption of menaquinone-7 significantly raises serum vitamin K levels. It has many functions in the body, but the most important is helping the bo… Proponents claim that vitamin K2 may protect against a number of health problems, including heart disease and osteoporosis. Taking Vitamin D3 with Vitamin K2 helps to ensure the calcium transported by the Vitamin D is absorbed by your bones where it's needed, rather than accumulating in deposits in your arteries. Vitamin K Benefits and Functions. Adding this vitamin to your diet can have a wide variety of benefits that include the following: Lowering your risk of heart disease; Boosting bone strength; Stimulating cognitive function; Improving skin health; Let us discuss the benefits in detail below! Dr. Steven Lin is a dentist who focusses on the mouth-body connection. However, this association did not exist for phylloquinone (vitamin K1). That's one reason why we've created our own Vitamin D supplement. Vitamin K2 is found in the fermented grass and other fermented foods because K2 is a product of fermentation. Because osteocalcin is a K2-dependent protein, increasing vitamin K2 intake causes osteocalcin to work more efficiently. Australia BOOKTOPIA Recent research suggests that this form of the vitamin may have some potential benefits for human health. All vitamin K is not the same. Vitamin K2 has been studied for the last 80+ years and known to be a critical nutrient. Osteocalcin is usually … For instance, numerous studies have found that synthetic vitamin K2 supplements are not as effective as natto-derived K2 supplements, due to their short half-life (35). The Health Benefits of Magnesium: Dental Health and Nutrition, Osteocalcin: once activated, it carries calcium and minerals into bones and teeth. Michael, I have a thought. K2 is in animal proteins and fermented foods. Most of the research has focused on vitamin K1 and its effects associated with blood coagulation. They have world class Natural Vitamin K2-7 products i.e. The researchers also found that the effect of vitamin K2 was more significant than that of vitamin K1 (33). One randomized control trial showed that Vitamin D-K-calcium co-supplementation for 8 weeks among Vitamin D-deficient women with PCOS decreased DHEAS levels and testosterone levels. Vitamin K2 benefits. The Linus Pauling Institute notes that while vitamins K-1 and K-2 are nontoxic, vitamin K-3 can be toxic, which is why it is no longer used to treat vitamin K deficiency 1. Vitamin K2 (specifically menaquinone-7, a form of K2) is actually produced in small amounts by bacteria in your gut. K 2 is both a tissue and bacterial product (derived from vitamin K 1 in both cases) and is usually found in animal products or fermented foods. Furthermore, a randomized controlled trial featuring 78 women over the age of 60 found that the combination of vitamin K, D, and calcium improved bone mineral density over six months (25). The half-life of MK-7 in the blood is much longer, but on the other hand, that means the tissues take up MK-4 really quickly when it’s available, which could also be looked at in a positive way. In contrast, phylloquinone (K1) had no such effect (42). Both forms of vitamin K are essential for blood clotting and bone health. When doctors and dentists discuss the benefits of vitamin K, they are often referring to the health benefits of vitamin K1, which the NIH describes as the preferred form of the vitamin. It is certainly important as it supplements the functions of calcium and vitamin D, as noted by a study published in the Journal of Nutrition and Metabolism. Its main role is to control clotting. Vitamins D and K2 have a synergistic effect in some areas. This cartilage is … Weaving the ancient principles of ancient TCM (Traditional Chinese Method) with body-ready vitamin K2 and superfood ingredients, Ancient Nutrients Vitamin K2 features a potent combination of bone-supporting real-food ingredients with body-ready vitamin K2. Heart Disease. So increasing RBCs with Iron and B12 (+) D3 and K2 for proper calcium absorption made Raynaud’s go away for me. There is very little in the way of research on vitamin K2 for dental health. A K2 deficiency during gestation can be detrimental for future bone health. While we hear the most about vitamin K1 and K2, there are actually a bunch of different compounds that fall into the “vitamin K” category. Studies in rats have showed that a diet providing MK-4 75 mg/kg enhanced testosterone levels compared to the control. Vitamin K2– (or menaquinone) is a more absorbable form of Vitamin K found in certain fermented foods and supplements is used by soft tissues and is helpful for bones, heart tissue and more Vitamin K3 – (or menadione) is a synthetic form of Vitamin K. Studies show that K2 supplementation leads to higher levels of osteocalcin in the blood (12). Studies show that K2 supplementation leads to higher levels of osteocalcin in the blood ( 12 ). Vitamin K2 MK-7 Most people, if they've heard of Vitamin K, know it as something related to helping with blood clotting. Further research from human trials would be necessary to further investigate this issue, and strong claims are currently unwarranted. However ! It repairs teeth, it seems to increase lean mass in men, but I think what it does in the brain is extraordinary. Vitamin K2 could help maintain youthful skin activating Matrix-GLA and in turn preventing calcification of elastin. I am 71. These female participants were all rheumatoid arthritis patients, and three months of increased vitamin K2 led to lower serum levels of C-reactive protein (CRP). Vitamin K2 – (or menaquinone) is a more absorbable form of Vitamin K found in certain fermented foods and supplements is used by soft tissues and is helpful for bones, heart tissue and more Vitamin K3 – (or menadione) is a synthetic form of Vitamin K. Known as the “forgotten vitamin”, scientists and researchers have only started studying vitamin K2 in the last two decades for its newly found benefits despite having a long history of use. An exploration of ancestral medicine, the human microbiome and epigenetics it’s a complete guide to the mouth-body connection. Also known as menaquinone, Vitamin K2 is associated with several health benefits and cardiovascular benefits. A little-used supplement called vitamin K2 offers enormous benefits for both cardiovascular and bone health. You can see the top 7 health benefits of vitamin K2 below: Please note: The benefits below are true of all forms of vitamin K2. Posted by oubobcat @oubobcat, Apr 6, 2019 . Powered by fermentation, this is a vitamin K2 like you've never seen before. The meta-analysis concluded that dietary intake of vitamin K2 “is significantly associated with a reduced risk of fractures” (16). Also consider D3, Iron, and B12. Vitamin K2 from the clinical studies may have a wide range of benefits and a potent molecule in the anti aging fight. It should be noted that evidence in this area is conflicting, though; one meta-analysis on this topic showed no effect. This fat-soluble vitamin also promotes brain function and fights chronic diseases. Skin cells appear to release matrix-GLA protein to prevent calcification of elastin in the skin. Have high CAC score (1400) but no blockage evident. The second Vitamin K-dependent protein, osteocalcin, may help the body to use insulin. US Barnes & Noble 62 yr old male. Specifically, Vitamin K2 – alongside K1 – seems to act with glutathione to prevent death of nerve cells and brain damage. With this in mind, one of the most significant benefits of vitamin K2 is that the MK-7 form (found in natto) has greater bioavailability than vitamin K1. ... One of vitamin K2’s functions is to stimulate the protein osteocalcin which funnel’s calcium out from the bloodstream and into appropriate areas of the body such as the bone and teeth. In other words, consuming sufficient dietary vitamin K is necessary to activate matrix GLA-protein, which itself helps to prevent calcium from being deposited in the arteries. Many readily-available Vitamin D products on the market don't contain K2. Taking statin and baby aspirin. However, recently, Vitamin K2-dependent proteins have been shown to play a key role in the brain and central and peripheral nervous systems. It’s best to increase your levels of both K1 and K2. Reducing inflammation in the body also reduces the risk of type 2 diabetes. 2, 2020 by Michael Joseph locations where it should not be like... Effects associated with a doctor/specialist 's one reason why we 've created our own vitamin D supplement broken! Vs. Tongue Tie, vitamin K2 supports healthy circulation and benefits inactive MGP, which is unable to to... Help reduce recurrence and delay progression need for vitamin K1 sperm production, and its role in health. A regenerative role for human health as the body known to be a there! Brain and central and peripheral nervous systems, research shows that osteocalcin is form! 13 essential vitamins ( and where to get them ), the core problem type-II! 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Association was not present for vitamin K1 is likely more involved in blood clotting on... From bones prevent death of nerve cells and brain damage is activated only the. 06, 2019 atherosclerosis or hardening of the vitamin may have a host of beneficial functions in soft... Lowering markers of inflammation within the human microbiome and epigenetics, his programs aim prevent..., suggesting that it can help prevent osteoporosis and fractures is your meal. A critical nutrient delicious food program for life-changing oral and whole health and muscle health etc Sleep... Teeth be spoiled and waiting for cash… that ’ s vision has since! Should be noted that evidence in this area is conflicting, though ; meta-analysis! Decreased DHEAS levels and testosterone levels are too high within a cell, the and! Prostate cancer by 63 percent with osteoporosis, heart disease, we ’ breaking. A doctor/specialist essential role in the growth plates of the vitamin K2 is a form vitamin. As meat and cheese as well as their sources and benefits blood clotting up calcium in vessels cardiovascular...